| 120例含苯丙醇胺药物致不良反应分析 |
| |
| 引用本文： | 姜成丽.120例含苯丙醇胺药物致不良反应分析[J].中国药房,2001,12(5):296-297. |
| |
| 作者姓名： | 姜成丽 |
| |
| 作者单位： | 重庆医科大学附属第二医院药剂科, |
| |
| 摘 要： | 目的 :探讨含苯丙醇胺 (PPA)药物不良反应的特点。方法 :用文献计量学方法对近9年国内公开报道的含PPA药物致不良反应120例文献进行分析。结果 :120例含PPA药物所致不良反应中 ,心血管系统反应66例 (占55 6 % ) ,神经系统反应13例 (占10 8 % ) ,过敏反应29例 (占24 2 % ) ,其中4例 (占3 3 % )致过敏性休克 ,1例 (占0 8 % )严重过敏致死 ;A型反应89例 ,B型反应31例。结论 :含PPA药物的安全性存在争议。
|
| 关 键 词： | 苯丙醇胺 药物不良反应 文献分析 |
| 文章编号： | 1001－ 0408（ 2001） 05－ 0296－ 02 |
| 修稿时间： | 2001年2月2日 |
Analysis of ARDs Induced by PPA-containing Drugs in 120 Cases |
| |
| JIANG Chengli.Analysis of ARDs Induced by PPA-containing Drugs in 120 Cases[J].China Pharmacy,2001,12(5):296-297. |
| |
| Authors: | JIANG Chengli |
| |
| Abstract: | OBJECTIVE:To investigate the characteristics of ARDs induced by PPA-containing drugs in 120 cases METHODS:Using literature metrological method,120 cases of ARDs induced by PPA-containing drugs,reported in China in recent 9 years,were analysed RESULTS:Of 120 cases,66 had cardiovascular reactions(55 6%),13 had reactions of nervous system(10 8%),29 had allergic reactions(24 2%) Among 24 cases of allergic reactions,4 revealed allergic shock(3 3%)and one died of severe allergic shock(0 8%) The reaction of 89 cases were classified as A-type reaction and that of 31 cases as B-type reaction CONCLUSION:There is a controversy over the safty of PPA-containing drugs |
| |
| Keywords: | phenylpropanolamine adverse reaction of drug analysis of literature |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
