九代清源口服液增强反复呼吸道感染患儿免疫功能的临床实验研究

目的：探讨九代清源口服液在增强反复呼吸道感染患儿免疫功能中的作用。方法：将１００例ＲＲＩ患儿随机分为２组，即常规治疗组和九代清源口服液辅助治疗组（简称九代组），分别于治疗前、治疗后抽取静脉血检测Ｔ淋巴细胞亚群（ＳＰ法）、ＮＫ细胞活性（ＭＴＴ法）、ｓＩＬ－２Ｒ（ＥＬＩＳＡ法）、ＩｇＧ、ＩｇＡ、ＩｇＭ（透比浊法）。结果：ＲＢＩ患儿治疗前ＣＤ３＾＋、ＣＤ４＾＋、ＣＤ４＾＋／ＣＤ８＾＋、ＮＫ细胞活性及ＩｇＧ、ＩｇＡ显著降低，ＣＤ８＾＋、ＩｇＭ和ｓＩＬ－６Ｒ显著升高常规治疗指标明显好转，与正常对照组比较，仍有显著差异（Ｐ〈０．０５）；九代组治疗后有所恢复，但与正常对照组比较均无显著性差异（Ｐ〉０．０５）。结论：九代清源口服液具有较强的免疫调节作用，可明显增强ＲＲＩ患儿的细胞和体液免疫功能。

Clinical and experimental study on Jiudaiqingyuan oral liquid in strengthening immunolgic function of children with recurrent respiratory infection(RRI)

Objective:To explore the effect of Jiudaiqingyua n oral liquid in strengthening immunologic function of children with RRI.Methods:100 children with RRI were randomly divided into two grou ps:the routine treatment group(RTG) and the group treated with Jiudaiqingyuan o r al liquid (JDG).Venous blood was drawn before and after treatment to detect T ly mphocyte subsets(SP method),NK cell activity (MTT method),sIL-2R(ELISA method), IgG,IgA,IgM(transmission turbidimetric method).Results:CD 3+，CD4+，CD4+/CD8+,NK cell activity and IgG,IgA of the children with R RI were notably lower and CD8+、IgM、sIL-6R markly higher before treatment.Th ese indexes recovered to some extent af ter routine treatment but were still significantly different from those of norma l controls(P＜0.05).The indexes of JDG recovered notably after treatment whi ch were not significantly different from those of normal control(P＞0.05).Conclusion:Jiudaiqingyuan oral liquid has strong effect on immunologic regulation.It may markly enhance cellular and humoral function of children with RRI.