以急性脑膜炎为首发症状的莱姆病：附一例报告

为加强对莱姆病的认识，报道１例以急性脑膜炎为首发症状、经血清学检测（ＥＬＩＳＡ及Ｗｅｓｔｅｒｎｂｌｏｔｉｎｇ两种方法）证实为神经莱姆病的诊治经过。表明北京地区有莱姆病存在。如发现淋巴细胞增多性脑膜炎而原因不明时，神经莱姆病应作为鉴别诊断之一，及时送检血清及脑脊液莱姆病的抗体检测将有助于诊断。

LYME NEUROBORRELIOSIS WITH ACUTE MENINGITIS AS THE PRESENTING MANIFESTATION: REPORT OF A CASE

To enhance the understanding of Lyme disease, a case of Lyme neuroborreliosis with acute meningitis as the presenting manifestation was reported. The diagnosis was confirmed by elevated serum antibody response to B.burgdorferi using both ELISA and Western blotting, excluding other causes of neurological abnormalities and the typical response of our patient to antibiotics. This case indicates the existence of Lyme disease in Beijing area. If the etiology of a meningitis with lymphocytic pleocytosis is not known, it is important that Lyme neuroborreliosis should be considered as one of the differential diagnoses and detection of antibody to B. burgdorferi in serum and cerebrospinal fluid performed in time. A brief review of the literature including epidemiology, clinical menifestations, diagnosis and treatment of Lyme disease was made.