| 肉豆蔻属植物化学成分和药理活性研究进展 |
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| 引用本文： | 张勇,张娟娟,康文艺,闫文义.肉豆蔻属植物化学成分和药理活性研究进展[J].中国中药杂志,2014,39(13):2438-2449. |
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| 作者姓名： | 张勇 张娟娟 康文艺 闫文义 |
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| 作者单位： | 河南大学 中药研究所, 河南 开封 475004;河南大学 中药研究所, 河南 开封 475004;河南大学 中药研究所, 河南 开封 475004;河南大学 中药研究所, 河南 开封 475004 |
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| 基金项目： | 河南省科技厅重点攻关项目（132102310261） |
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| 摘 要： | 肉豆蔻科肉豆蔻属植物全球约有120余种，分布于南亚，从玻利尼西亚西部、大洋洲、印度东部至菲律宾。国内外学者已从该属植物中分离得到164个化合物，其中大部分是木脂素，此外还包括苯丙素、黄酮和酚类成分等，具有抗菌、抗炎、抗氧化、抗癌、降血糖、保肝等生物活性。该文总结了该属植物的化学成分和药理活性研究进展，为综合利用与深入开展该药用植物资源提供参考依据。
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| 关 键 词： | 肉豆蔻属 化学成分 药理活性 研究进展 |
| 收稿时间： | 2013/11/12 0:00:00 |
Advances of chemical constituents and pharmacological activities of Myristica genus |
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| ZHANG Yong,ZHANG Juan-juan,KANG Wen-yi and YAN Wen-yi.Advances of chemical constituents and pharmacological activities of Myristica genus[J].China Journal of Chinese Materia Medica,2014,39(13):2438-2449. |
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| Authors: | ZHANG Yong ZHANG Juan-juan KANG Wen-yi and YAN Wen-yi |
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| Institution: | Institute of Natural Medicines, He'nan College, Kaifeng 475004, China;Institute of Natural Medicines, He'nan College, Kaifeng 475004, China;Institute of Natural Medicines, He'nan College, Kaifeng 475004, China;Institute of Natural Medicines, He'nan College, Kaifeng 475004, China |
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| Abstract: | The genus Myristica (Myristicaceae) consists of 120 species, which were distributed in South Asia, from west Polynesia, Oceania, eastern India to the Philippines. Phytochemical studies showed that 164 compounds including a majority of lignans,along with phenglpropanoids, flavonoids and phenolics, have been isolated from this genus, which exhibited anti-microbial, anti-inflammatory, anticancer, hyperglycemic and hepatic protective activities. This article summarizes research progress of the chemical compositions and their pharmacological activities from this genus, which could provide reference for the in-depth development and utilization of the Myristica plants. |
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| Keywords: | Myristica genus chemical constituents pharmacological activities advances |
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