高度近视PRK后重度角膜上皮下浑浊5年随访

目的 了解高度近视PRK后重度角膜上皮下浑浊长期变化情况。对象与方法 95年3月－8月在我院眼科激光中心行PRK手术的高度超高度近视患者中，有部分患眼发生了Ⅲ级角膜上皮下浑浊，对其中7例7眼随访5年。结果 全部7眼在3月时角膜上皮下浑浊达到高峰，3－12月虽经局部滴用皮质类固醇，角膜浑浊也无改善，随访至3年时角膜上皮下浑浊开始出现变化，4年时全部7眼均有不同程度的减轻，无1眼保持在Ⅲ级，其中4眼降至Ⅱ级，角膜渐显透明，5年时4眼降至Ⅰ级。结论 PRK术后重度角膜上皮下浑浊有随着时间的推移而逐渐减轻的趋势。

Follow up 5 years of manifest subepithelial corneal haze after photorefractive keratectomy for hypermyopia

Objective To observe the change of corneal haze over a long period of time after PRK for hypermyopia.Methods significant corneal haze was observed in 7 eyes of hypermyopia treated with PRK and follow up 5 years.Results subepithelial opacification of the anterior stroma in all 7 myopic eyes gradually increased after PRK,reaching a maximum at 3 to 6 months:moderate haze.Although a standard topical corticosteroid regimen was used,the opacification was continue.It began to change as following up to 3 years.The corneal began to clear up slowly,up to 4 years there were no eyes stayed in moderate haze,4 of 7 eyes decreased from moderate to mild haze,3 eyes to trace,and at the 5 years 4 eyes decreased to trace.Conclusion The corneal haze after PRK of hypermyopia had a tendency that clear up gradually.