| 薄荷醇与冰片的促透作用 |
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| 引用本文： | 王晖,许卫铭,王宗锐.薄荷醇与冰片的促透作用[J].中草药,1997,28(2):93-95. |
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| 作者姓名： | 王晖 许卫铭 王宗锐 |
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| 作者单位： | 广东医学院药理教研室!湛江，524023 |
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| 摘 要： | 研究薄荷醇和冰片对双氯灭痛的经皮透过作用，发现二者均可使双氯灭痛的透过量增加，但作用较氮酮为弱；同时发现二者的滞后时间比氮酮显著为短。结果提示，薄荷醇和冰片可望作为促透剂在某些药物的透皮给药制剂中得到应用。
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| 关 键 词： | 薄荷醇 冰片 氮酮 双氯灭痛 促透剂 |
| 收稿时间： | 1995/11/27 0:00:00 |
Effect of 1-Menthol and Synthetic Borneol on Enhanced Percutaneous Penetration |
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| WANG Hui,XU Wei-ming and WANG Zong-rui.Effect of 1-Menthol and Synthetic Borneol on Enhanced Percutaneous Penetration[J].Chinese Traditional and Herbal Drugs,1997,28(2):93-95. |
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| Authors: | WANG Hui XU Wei-ming and WANG Zong-rui |
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| Institution: | Department of Pharmacology, Guangdong Medical College, Zhenjiang;Department of Pharmacology, Guangdong Medical College, Zhenjiang;Department of Pharmacology, Guangdong Medical College, Zhenjiang |
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| Abstract: | Effect of 1-menthol and synthetic borneol on percutaneous penetration of diclofenac sodium was examfined.It was found that both 1-menthol and synthetic borneol could increase percutaneous penetration of diclofenac sodium,but much weaker when compared with azone,and with shorter lag times(Tlag).The rusultsindicated that 1-menthol and synthetic borneol could he used in transdermal delivery system of some drugs astransdermal enhancers. |
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