Pattern of labeling of poly (A)-associated RNA in the CA3 region of rat hippocampus during training |
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Authors: | Aroldo Cupello,Holger Hyd n |
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Affiliation: | Aroldo Cupello,Holger Hydén |
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Abstract: | Newly synthesized poly (A)-associated mRNA was analysed in the hippocampal CA3 pyramidal nerve cells in rats subjected to training to reverse handedness. The nerve cells of trained animals showed a smaller percentage of poly (A)-associated mRNA than did the active controls. However, a specific fraction of this poly (A) hippocampal RANA with a SE value of around 25 was reproducibly stimulated. This qualitative nerve cell mRNA change is discussed in relation to similar changes in the protein pattern as a function of training. |
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Keywords: | mRNA poly (A)-associated RNA learning hippocampus |
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