经阴道彩色多普勒超声对不孕症的子宫内膜及子宫血流动力学变化研究

目的:经阴道彩色多普勒超声观察各种不孕症的子宫内膜增殖变化及子宫动脉血流动力学变化,研究子宫动脉RI(Resistane lndex)值与不孕、不育关系。方法:经阴道彩色多普勒超声观察原发不孕15例、继发不孕15例和正常组15例月经周期子宫内膜增殖变化及子宫动脉血流,对照统计各组子宫内膜厚度与子宫动脉RI值的相关关系及各组之间子宫内膜厚度和子宫动脉RI值的差异。结果:正常组近排卵期至黄体初期子宫内膜快速增厚,子宫动脉RI值下降。原发不孕、继发不孕组近排卵期至黄体初期子宫内膜增厚缓慢,子宫动脉RI值增高。统计分析结果,月经第6~20天子宫动脉RI值与子宫内膜厚度呈负相关性(|r|≥0.5)。月经第10天后,正常组与各不孕组间子宫内膜厚度、子宫动脉RI值有显著性差异(P<0.01),原发不孕组与继发不孕组之间子宫内膜厚度、子宫动脉RI值无显著性差异。结论:月经周期中子宫动脉RI值反映卵巢激素水平,子宫内膜厚度变化与子宫动脉RI值呈负相关性,子宫动脉RI值增高可能是不孕症发病主要原因。

Hemodynamic research on endometrium and uterus with sterility by transvaginal color Doppler ultrasound

Objective:By observing the proliferation of endometrium and hemodynamics with sterility by transvaginal Doppler ultrasound,to research the relationship between resistance index of uterine artery and sterility.Methods:The proliferation of endometrium and the hemodynamic changes of uterine artery were observed by transvaginal color Doppler ultrasound in 15 cases of primary sterility,15 cases of secondary sterility and 15 cases of normal women.And the correlation and difference between the thickness of endometrium and the resistance index of uterine artery were analyzed statistically.Results:The endometrium was quickly thickened and the resistance index of uterine artery was decreased simultaneously from the ovulation phase to the early luteal phase in the normal group.The endometrium was slowly thickened and the resistance index of the uterine artery was increased from the ovulation phase to the early luteal phase in the primary and secondary sterility groups.The resistance of uterine artery and the thickness of the endometrium were correlated strictly from the 6th to 20th day of menstrual cycle.The thickness of endometrium and resistance index of uterine artery revealed a significant difference between normal group and sterility group,and revealed no difference between primary sterility group and secondary group.Conclusion:The thickness of endometrium is negatively correlated with resistance index of uterine artery,so increase of resistance index of uterin artery might be the main cause of the sterility.