| 探讨老年胃癌患者胃液中TNF-α,CA19-9和CEA联合检测的临床价值 |
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| 引用本文： | 李明,刘顺英,李卫东,江洁,潘金泉,叶正龙,常尉文,张文清.探讨老年胃癌患者胃液中TNF-α,CA19-9和CEA联合检测的临床价值[J].世界华人消化杂志,2006,14(25). |
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| 作者姓名： | 李明 刘顺英 李卫东 江洁 潘金泉 叶正龙 常尉文 张文清 |
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| 作者单位： | 1. 江苏油田总医院消化内科,江苏省扬州市,225261
2. 东南大学附属中大医院消化科,江苏省南京市,210009 |
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| 摘 要： | 目的:探讨老年患者胃液中TNF-α,CA19-9和CEA联合检测对胃癌的诊断价值．方法:采用放射免疫技术测定42例胃癌和61例良性胃病老年患者胃液中TNF-α,CA19-9和CEA浓度．结果:胃癌组胃液中TNF-α,CA19-9和CEA的浓度显著高于良性胃病组(8．96±2．10 mg／L vs 4．92±1．24．5．66±1．25 mg／L;59．47±10．58 IU／L vs 36．89±11．23．38．73±9．23 IU／L; 31．68±5．58 mg／L vs 1'．55±3．82,19.42±5．19 mg／L,均P<0．001);胃癌组联合检测胃液中TNF-α,CA19-9和CEA,其敏感度和特异度分别97．4％,89．3％,均明显高于单项指标的敏感度和特异度．结论:联合检测胃液中TNF-α,CA19-9和CEA能有助于提高胃癌的诊断．
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| 关 键 词： | 固相免疫放射分析法 胃癌 肿瘤坏死因子α 糖链抗原19-9 癌胚抗原 联合检测 |
Clinical value of combined detection of tumor necrosis factor-α, carbohydrate antigen 19-9 and carcinoembryonic antigen in gastric fluid of elderly patients with gastric cancer |
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| Ming Li,Shun-Ying Liu,Wei-Dong Li,Jie Jiang,Jin-Quan Pan,Zheng-Long Ye,Wei-Wen Chang,Wen-Qing Zhang.Clinical value of combined detection of tumor necrosis factor-α, carbohydrate antigen 19-9 and carcinoembryonic antigen in gastric fluid of elderly patients with gastric cancer[J].World Chinese Journal of Digestology,2006,14(25). |
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| Authors: | Ming Li Shun-Ying Liu Wei-Dong Li Jie Jiang Jin-Quan Pan Zheng-Long Ye Wei-Wen Chang Wen-Qing Zhang |
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| Abstract: | |
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| Keywords: | Immunoradiometric assay Gastric cancer Tumor necrosis factor-alpha Carbohydrate antigen 19-9 Carcinoembryonic antigen antigen Combined detection |
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