| “从菌论治”结直肠癌的初步探讨＊ |
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| 引用本文： | 田婷婷,刘璇,陈果,杨柱,龙奉玺,唐东昕. “从菌论治”结直肠癌的初步探讨＊[J]. 世界科学技术-中医药现代化, 2020, 22(7): 2519-2523 |
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| 作者姓名： | 田婷婷 刘璇 陈果 杨柱 龙奉玺 唐东昕 |
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| 作者单位： | 贵州中医药大学 贵阳 550002;贵州省中医肿瘤传承与科技创新人才基地 贵阳 550002;贵州中医药大学 贵阳 550002;贵州省中医肿瘤传承与科技创新人才基地 贵阳 550002 |
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| 基金项目： | 五年制本科人才培养模式改革（中医学）（教高函[2015]3号）：？,负责人：？;基于“循环肿瘤细胞”探讨蟾灵膏对HIF-1α/TGF-β介导的EMT效应在结直肠癌肝转移中的作用机制（81860819）;中医肿瘤学研究生工作站项目（黔教研合JYSZ字[2014]018）;贵州省高层次创新型人才培养计划（百层次）[黔科合人才（2016）4032号];贵州省中医肿瘤传承与科技创新人才基地（黔人领发[2018]3号）;贵州省杨柱“中医肿瘤学”研究生导师工作室项目（黔教研合GZS字[2016]08）;抗肿瘤药蟾灵膏的临床前研究（黔科合SY字[2014]3008-1号）。 |
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| 摘 要： | 近年来,关于肠道菌群失衡致结直肠癌的研究成了热点,而中药治病多以口服形式进入肠道,直接与菌群相互作用发挥疗效,在优化菌群结构、保护肠道微生态平衡方面的作用不容小觑。本文以中医理论为指导,结合结直肠癌各证型中菌群变化特点,探讨中药与菌群相互作用治疗结直肠癌的积极作用,以此展望中药调整菌群治疗结直肠癌的研究方向。
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| 关 键 词： | 结直肠癌 肠道菌群 中医理论 中医药 |
| 收稿时间： | 2020-02-17 |
| 修稿时间： | 2020-08-01 |
Preliminary Study on Treatment of Colorectal Cancer by Bacteriology |
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| Tian Tingting,LiuXuan,Chen Guo,Yang Zhu,Long Fengxi and Tang Dongxin. Preliminary Study on Treatment of Colorectal Cancer by Bacteriology[J]. World Science and Technology—Modernization of Traditional Chinese Medicine and Materia Medica, 2020, 22(7): 2519-2523 |
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| Authors: | Tian Tingting LiuXuan Chen Guo Yang Zhu Long Fengxi Tang Dongxin |
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| Affiliation: | Guizhou University of traditional Chinese Medicine, Guiyang, Guizhou 550002, China,Guizhou University of traditional Chinese Medicine, Guiyang, Guizhou 550002, China,Guizhou University of traditional Chinese Medicine, Guiyang, Guizhou 550002, China,Guizhou University of traditional Chinese Medicine, Guiyang, Guizhou 550002, China;Guizhou Province TCM Tumor Inheritance and Technology Innovation Talent Base, Guiyang 550002, China,Guizhou University of traditional Chinese Medicine, Guiyang, Guizhou 550002, China;Guizhou Province TCM Tumor Inheritance and Technology Innovation Talent Base, Guiyang 550002, China,Guizhou University of traditional Chinese Medicine, Guiyang, Guizhou 550002, China;Guizhou Province TCM Tumor Inheritance and Technology Innovation Talent Base, Guiyang 550002, China |
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| Abstract: | In recent years, the research on colorectal cancer caused by imbalance of intestinal flora has become a hot topic. However, traditional Chinese medicine is mostly used in the treatment of intestinal tract by oral administration, which directly interacts with the flora to play a role in optimizing the flora structure and protecting the intestinal microecological balance. Guided by the theory of traditional Chinese medicine and combined with the characteristics of flora changes in various syndromes of colorectal cancer, this paper discusses the active role of interaction between traditional Chinese medicine and flora in the treatment of colorectal cancer, and looks forward to the possible research direction of traditional Chinese medicine in regulating flora in the treatment of colorectal cancer. |
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| Keywords: | Colorectal cancer Intestinal flora Traditional chinese medicine theory Traditional chinese medicine |
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