虎杖叶胶囊联合手法复位治疗良性阵发性位置性眩晕的临床疗效分析

目的 中医理论认为痰湿中阻与肝阳上亢是形成眩晕的主要原因,本课题通过使用能够祛风息痰、平肝潜阳的虎杖叶胶囊联合手法复位治疗良性发作性位置性眩晕(BPPV),并观察临床疗效。方法 以BPPV的患者为研究对象,设立单纯手法复位治疗组及虎杖叶胶囊联合手法复位治疗组。分别在治疗前、治疗2周及治疗4周时采用头晕残障问卷(DHI)评估患者残余症状中躯体(P)、情绪(E)、功能(F)状态,评价虎杖叶胶囊联合手法复位对BPPV的临床疗效。结果 治疗前,2组的DHI评分中的P、E、F评分、总分(T)之间无明显统计学差异(P均≥0.05)；治疗2周后,单纯手法复位治疗组与虎杖叶胶囊联合手法复位治疗组的DHI评分中的P、E、F、T评分均有显著性差异(P均<0.001)；这种显著性差异在治疗4周时仍然存在(P均<0.01)。结论 本研究表明具有祛风息痰、平肝潜阳作用的虎杖叶胶囊联合手法复位治疗对改善BPPV症状较单纯手法复位疗效更佳,为改善BPPV患者临床症状提供新的思路与方法。

Clinical efficacy of Huzhangye capsule combined with manual reduction on benign paroxysmal positional vertigo

Objective To observe the clinical efficacy of Huzhangye capsule (dispelling pathogenic wind and eliminating phlegm, and suppressing hyperactive liver and subsiding yang) combined with manual reduction on benign paroxysmal positional vertigo (BPPV). Methods A total of 70 patients with BPPV were prospectively enrolled and randomly divided into simple manual reduction group (n=35) and Huzhangye capsule combined with manual reduction group (n=35). The physical, emotional and functional status in residual symptoms were assessed by dizziness handicap inventory (DHI) before treatment, 2 weeks and 4 weeks after treatment. Results There were no significant differences in physical, emotional and functional scores, or total score in DHI between the two groups before treatment (all P>0.05). After 2 weeks and 4 weeks of treatment, the physical, emotional and functional scores, and total score in DHI in Huzhangye capsule combined with manual reduction group were significantly lower than those in the manual reduction group (all P<0.01). Conclusion Huzhangye capsule combined with manual reduction is more effective in improving the symptoms of BPPV than manual reduction alone.