Distribution of dynorphin B and methionine-enkephalin in the mouse hippocampus: influence of genotype |
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| Authors: | J H van Daal H E Zanderink B G Jenks J H van Abeelen |
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| Affiliation: | Department of Animal Physiology, University of Nijmegen, The Netherlands. |
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| Abstract: | Immunohistochemical techniques were used to localize dynorphin B and methionine-enkephalin in the mouse hippocampus. Methionine-enkephalin-like immunoreactivity was found within the somata of interneurons distributed mainly in and around the CA1 stratum pyramidale and stratum granulosum as well as in the mossy fibers. Dynorphin B appeared to be confined to the mossy fiber pathway. In addition, we observed a difference between the inbred mouse strains DBA/2 and C57BL/6 with regard to the areas of the dynorphinergic mossy fiber projections: the intra- and infrapyramidal terminal fields were larger in the latter group. |
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