| 大丁草中抗菌活性成分的研究 |
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| 引用本文： | 谷黎红,王素贤,李铣,朱廷儒.大丁草中抗菌活性成分的研究[J].药学学报,1987,22(4):272-277. |
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| 作者姓名： | 谷黎红 王素贤 李铣 朱廷儒 |
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| 作者单位： | 沈阳药学院天然药物研究室
(谷黎红，王素贤，李铣)，沈阳药学院天然药物研究室(朱廷儒) |
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| 摘 要： | 从菊科植物大丁草Gerbera anandvia(L.)Sch Bip.(Leibnitzia anandria(L.)Nakai)全草中分离出十二种化合物。经化学反应及光谱分析鉴定、确定了其中九个化合物的结构。共中晶Ⅷ(大丁纤维二糖甙,5-methyl-coumarin-4-cellobioside)和晶Ⅸ(大丁龙胆二糖甙,5-methyl-coumarin-4-gentiobioside)为二个新的天然产物。其它七种化合物为大丁双香豆特(Ⅰ)、大丁甙元(Ⅱ)、琥珀酸(Ⅲ)、大丁甙(Ⅴ)、木犀草素7-β-D-葡葡糖甙(Ⅵ)、蒲公英赛醇(Ⅺ)和β-谷甾醇(Ⅻ)。其中晶Ⅰ,Ⅱ,Ⅲ,Ⅷ和Ⅸ显示了不同程度的抗菌活性。
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| 关 键 词： | 大丁草 香豆精 抑菌活性 |
| 收稿时间： | 1986-06-25 |
STUDIES ON ANTIBACTERIAL CONSTITUENTS FROM GERBERA ANANDRIA (L.) SCH. BIP. |
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| GU Li-Hong,WANG Su-Xian,LI Xian and ZHU Ting-Ru.STUDIES ON ANTIBACTERIAL CONSTITUENTS FROM GERBERA ANANDRIA (L.) SCH. BIP.[J].Acta Pharmaceutica Sinica,1987,22(4):272-277. |
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| Authors: | GU Li-Hong WANG Su-Xian LI Xian and ZHU Ting-Ru |
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| Abstract: | Twelve compounds have been isolated from Gerbera anandria(L.) Sch. Bip. Among them, nine were elucidated by chemical correlations and spectralanalysis. They are 3,3'-methenebi (4-hydroxy-5-methyl-coumarin) (Ⅰ), 4-hydroxy-5-methyl-coumarin(Ⅱ), succinic acid(Ⅲ), 5-methyl-coumarin-4-glucoside(Ⅴ), luteolin-7-glucoside(Ⅵ), 5-methyl-coumarin-4-cellobioside(Ⅷ), 5-methyl-coumarin-4-gentiobioside(Ⅸ), taraxerol(Ⅺ) and β-sitosterol(Ⅻ). Both Ⅷ and Ⅸ are new compounds. Ⅰ, Ⅱ, Ⅲ, Ⅷ and Ⅸ showed certain antibacterial activities. |
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| Keywords: | Gerbera anandria (L ) Sch Bip Coumarin Antibacteria activities |
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