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Poly (ADP-ribose) polymerase inhibitor reduces heart ischaemia/ reperfusion injury via inflammation and Akt signalling in rats
引用本文:SONG Zhao-feng,CHEN Dong-yu,DU Bo,JI Xiao-ping. Poly (ADP-ribose) polymerase inhibitor reduces heart ischaemia/ reperfusion injury via inflammation and Akt signalling in rats[J]. 中华医学杂志(英文版), 2013, 126(10): 1913-1917
作者姓名:SONG Zhao-feng  CHEN Dong-yu  DU Bo  JI Xiao-ping
作者单位:[1]Department of CardiologyTaian Central Hospitall Taian, Shandong271000, China [2]Department ofRheumatologyTaian Central Hospitall Taian, Shandong271000, China [3]Department of Cardiology, Shandong University Qilu Hospital, Jinan,Shandong 250012, China
基金项目:This,study,was,supported,by,grants,from,the,Natural,Science,Foundation,of,Shandong,Province,China(项目编号:ZR2010HM069)the,Technology,Development,Projects,of,Taian,City(项目编号:20093077)
摘    要:Background Poly (ADP-ribose) polymerase (PARP) has been proposed to play an important role in the pathogenesis of heart ischaemia/reperfusion (I/R)injury.3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-1(2H)-i...

关 键 词:缺血  再灌注损伤  心脏功能  信号通路  Akt  聚合酶  大鼠  酶抑制剂  核糖

Poly (ADP-ribose) polymerase inhibitor reduces heart ischaemia/reperfusion injury via inflammation and Akt signalling in rats
SONG Zhao-feng,CHEN Dong-yu,DU Bo and JI Xiao-ping. Poly (ADP-ribose) polymerase inhibitor reduces heart ischaemia/reperfusion injury via inflammation and Akt signalling in rats[J]. Chinese medical journal, 2013, 126(10): 1913-1917
Authors:SONG Zhao-feng  CHEN Dong-yu  DU Bo  JI Xiao-ping
Affiliation:1. Department of Cardiology, Taian Central Hospital, Taian, Shandong 271000, China
2. Department of Rheumatology, Taian Central Hospital, Taian, Shandong 271000, China
3. Department of Cardiology, Shandong University Qilu Hospital, Jinan,Shandong 250012, China
Abstract:
Keywords:heart ischaemia/reperfusion, poly (ADP-ribose) polymerase,3,4-dihydro-5-[4-(1-piperidinyl)butoxy]-l (2H)- isoquinolinone  Akt," inflammation
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