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Dexamethasone in the Treatment of Bronchopulmonary Dysplasia
Authors:FRANCA BENINI  F. F. RUBALTELLI  P. GRIFFITH  MARIELLA SALA  C. ZORZI
Affiliation:From the Department of Paediatrics, Universily of Padova, Italy
Abstract:Benini, F., Rubaltelli, F. F., Griffith, P., Sala, M. and Zorzi, C. (Department of Paediatrics, University of Padova, Italy). Dexamethasone in the treatment of bronchopulmonary dysplasia. Acta Paediatr Scand Suppl 360: 108, 1989.
Sixteen chronically ventilator-dependent newborns with BPD were treated with one or more cycles of dexamethasone (0.5 mg/kg/day). In 11 cases extubation was possible during the therapy period. Ventilatory parameters were lowered in 3 other newborns. FIO2, respiratory rate, PIP, and PEEP, assessed before and after dexamethasone administration, decreased in a statistically significant way. Our data confirm the utility of dexamethasone in the extubation in chronically ventilated infants with BPD.
Keywords:bronchopulmonary dysplasia    newborns    dexamethasone
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