Objective evaluation of the effect of autologous platelet concentrate on post-operative scarring in deep burns |
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Authors: | Hana Klosová Ji?í Štětinský Iveta Bryjová Stanislav Hledík Leo Klein |
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Institution: | 1. Burn Center, University Hospital Ostrava, 17. listopadu 1790, 708 52 Ostrava-Poruba, Czech Republic;2. VŠB-Technical University of Ostrava, 17. listopadu 15/2172, 708 33 Ostrava-Poruba, Czech Republic;3. Institute of Physics, Silesian University in Opava, Bezru?ovo nám. 13, 746 01 Opava, Czech Republic;4. Division of Plastic Surgery and Burns Unit, Charles University in Prague, Medical Faculty and Teaching Hospital in Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic;5. Faculty of Military Health Sciences, University of Defence, T?ebešská 1575, 500 01 Hradec Králové, Czech Republic |
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Abstract: | IntroductionThe healing of grafted areas after surgical treatment of deep burns frequently generates mutilating scars, and rises the risk of subsequent scar hypertrophy. Scar assessment based on clinical evaluation is inherently subjective, which stimulates search for objective means of evaluation.ObjectiveThe aim of this study was to objectively evaluate the effect of using autologous platelet concentrate (APC) in combination with split thickness skin grafting (STSG) on scarring processes following surgery of deep burns as compared with application of STSG alone.MethodSelected viscoelastic properties of 38 scars on 23 patients in total were examined using the Cutometer MPA 580 under controlled conditions for long-term outcomes 1, 3, 6 and 12 months after surgery following deep burns.ResultsThe findings of this study suggest that the STSG + APC combination reduces the time of scar viscoelastic properties recovery as compared with application of STSG alone. This was statistically significant for viscoelastic parameters R2 and Q1.ConclusionAPC has been advocated to enhance scarring after surgery of deep dermal and full thickness burns. We objectively demonstrated that the viscoelastic properties of scars treated with STSG + APC combination return more rapidly to the plateau state than areas treated with STSG only. |
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Keywords: | Burns assessment Scar Surgical treatment of deep burns Split thickness skin graft (STSG) Autologous platelet concentrate (APC) Skin viscoelasticity Cutometer |
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