Ex-PRESS引流器植入治疗原发性开角型青光眼的疗效

目的：观察Ex-PRESS青光眼引流器植入治疗原发性开角型青光眼的临床疗效。

方法：原发性开角型青光眼患者41例54眼分为研究组和对照组。研究组19例25眼，行Ex-PRESS青光眼引流器植入； 对照组22例29眼，行小梁切除术。比较两组患者平均手术时间、术后视力、浅前房、眼压、滤过泡及其他并发症的情况。

结果：研究组手术时间34.60±4.43min，术后1d浅前房1眼、前房出血1眼； 术后1wk高眼压2眼； 术后3mo视力下降1眼、功能性滤过泡24眼、眼压11.5±5.8mmHg。对照组手术时间44.37±3.00min，术后1d浅前房13眼、前房出血渗出12眼； 术后1wk高眼压8眼； 术后3mo视力下降6眼、功能性滤过泡25眼、眼压13.6±6.7mmHg。研究组术后并发症较少，眼压控制更低，术后视力影响、功能性滤过泡与对照组相当。

结论：Ex-PRESS青光眼引流器植入治疗原发性开角型青光眼手术时间缩短，术后浅前房、前房出血渗出并发症少，安全性高，疗效好。

Effect of Ex-PRESS filtration device in primary open angle glaucoma

AIM: To observe the effect of Ex-PRESS glaucoma filtration device in primary open angle glaucoma.

METHODS: Totally 41 patients(54 eyes)with primary open angle glaucoma were divided into two groups. Nineteen patients(25 eyes)in study group who underwent Ex-PRESS glaucoma filtration device implantation. Twenty-two cases(29 eyes)in control group who underwent trabeculectomy. Two groups were compared with the average operation time, post-operative visual acuity, anterior chamber, intraocular pressure, filtering bleb and other complications.

RESULTS: In study group operation time was(34.60±4.43)min, 1d postoperative shallow anterior chamber in 1 eye and hyphema in 1 eye, 1wk postoperative high intraocular pressure in 2 eyes, 3mo postoperative decreased vision in 1 eye, functional filtering blebs in 24 eyes, intraocular pressure was(11.5±5.8)mmHg. The control group operation time was(44.37±3.00)min, 1d postoperative shallow anterior chamber in 13 eyes, anterior chamber bleeding or exudation in 12 eyes, 1wk postoperative high intraocular pressure in 8 eyes, 3mo postoperative decreased vision in 6 eyes, functional filtering blebs in 25 eyes, intraocular pressure was(13.6±6.7)mmHg. The study group can shorten the operation time and reduce early postoperative shallow anterior chamber, lower intraocular pressure and incidence of anterior chamber exudation and bleeding. The study group can control postoperative IOP to a lower degree. Comparing with the traditional operation, the study group had equivalent effect in postoperative visual effects and functional filtering bleb.

CONCLUSION: Ex-PRESS glaucoma filtration device implantation in primary open angle glaucoma can shorten operation time, reduce the postoperative complications, and has the characteristics of high safety and good efficacy.