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Chondrosarcoma occurring in a patient with polyostotic fibrous dysplasia
Authors:Arthur A. De Smet M.D.  Henry Travers M.D.  James R. Neff M.D.
Affiliation:(1) Department of Pathology, The University of Kansas College of Health Sciences and Hospital, Kansas City, Kansas, USA;(2) Section of Orthopedic Surgery, The University of Kansas College of Health Sciences and Hospital, Kansas City, Kansas, USA;(3) Department of Diagnostic Radiology, The University of Kansas College of Health Sciences and Hospital, 39th at Rainbow Boulevard, 66103 Kansas City, KS, USA
Abstract:A 36-year-old white man with polyostotic fibrous dysplasia was found to have a high-grade chondrosarcoma arising from the left ilium. Although a left hemipelvectomy was performed, the patient subsequently developed sacral and pulmonary metastases and succumbed to his disease. This patient represents the first documented example of an unequivocally high-grade chondrosarcoma arising in an area of fibrous dysplasia without prior irradiation.
Keywords:Polyostotic fibrous dysplasia  Chondroarcoma
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