山东某高校大学生肠易激综合征与功能性便秘的流行病学调查

目的  调查山东某综合性大学大学生肠易激综合征（IBS）与功能性便秘（FC）的发病情况和相关因素分析。方法  2009年2～3月以自填式问卷的形式,随机抽样调查山东省某高校2500名本科生的IBS和FC的发病情况及相关因素。问卷包括罗马Ⅲ诊断问卷、医院焦虑与抑郁评分量表（HAD）、IBS生活质量问卷（IBS QoL）等。结果  共回收2126份有效问卷，IBS组167人，FC组115人。IBS和FC的发病率分别为7.85%和5.41%，IBS便秘型最多(36.5%), 其次是IBS 腹泻型(31.1%)和IBS混合型(23.9%)。FC中最常见的症状是排便需要明显用力（93.9%）和排便不尽感（93.0%）。IBS和FC组的焦虑和抑郁评分均高于正常对照组。在生活因素中，少运动和IBS有关，近一年的负性生活事件与FC有关。结论  山东省某高校大学生的IBS及FC的患病率低于国外报道水平。少运动和负性生活事件分别是IBS和FC发病的相关因素。

Prevalence of irritable bowel syndrome and functional constipation in college students from a university in Shandong Province

Objective  To estimate the prevalence and related factors of irritable bowel syndrome (IBS) and functional constipation (FC) in college students from a university in Shandong Province. Methods  From February to March 2009, 2500 college students were randomly selected to complete questionnaires including the Rome Ⅲ Questionnaire, Hospital Anxiety and Depression Scale, and Health Quality of IBS Questionnaire. Results   Valid responses were obtained from 2126 participants, in which 167 fulfilled criteria for IBS while 115 for FC. The prevalence rates of IBS and FC were 7.85% and 5.41% respectively. The IBS constipation subtype accounted for the majority( 36.5%), followed by IBS diarrhea (31.1%) and IBS mixed (23.9%). In the FC group, the main symptoms were straining (93.9%) and  sensation of incomplete evacuation during defecation(93.0%). Both IBS and FC groups showed higher anxiety and depression scores than the healthy controls. Among daily lifestyle factors, the low exercise level and recent negative life events indicated a higher risk for IBS and FC respectively. Conclusion  The prevalence rates of IBS and FC in the college students from the university in Shandong Province are lower than those in Western countries. The low exercise level and recent negative life events are the risk factors for IBS and FC respectively.