改道性结肠炎治疗进展

改道性结肠炎(diversion colitis,DC)是在结肠或回肠造口术后无粪流通过的旷置结肠段粘膜的非特异性炎症。尽管绝大多数肠道造口患者无症状,但几乎所有粪便改道患者均可出现DC。DC的临床症状主要有腹痛、里急后重、便血以及排粘液分泌物等,且随着肠管旷置时间延长而炎症可日渐加重,进而不同程度影响了这类患者的生活质量。然而,国内对DC的研究甚少,对DC的认识有限,因而还未引起临床医生的足够重视。鉴于此,我们在本文中对DC的表现及治疗方面的研究进展作一综述,以期能够提高临床对改道性结肠炎的认识,同时帮助临床医生做出更好的治疗决策。

Research progress in the treatment of diversion colitis

［Abstract］ Diversion colitis （DC） is a non?specific inflammation of the mucosa in the defunctioned part of the colon after colostomy or enterostomy. Although the majority of patients with intestinal stoma are asymptomatic， almost all patients with diverted stools could develop DC. The clinical symptoms of DC mainly include abdominal pain， tenesmus， colorectal bleeding， and discharge of mucus. Inflammation of mucosa could be aggravated with the prolonged of colon disused， which could affects the quality of life for these patients in different degrees. However， there were a few researches on DC and a lack of knowledge about it in China， so it has not attracted enough attention from clinicians. Given this， in this paper， the researches and advances in the clinical features， treatment， and patient management of DC were reviewed to improve the clinical understanding of DC and help doctors make better treatment decisions and management in the future.