代谢综合征患者颈总动脉扩张性、紧张度和僵硬度的检测

目的探讨代谢综合征患者颈总动脉扩张性、紧张度和僵硬度的变化。方法采用彩色多功能超声诊断仪对33例正常人、76例非代谢综合征患者和83例代谢综合征患者颈总动脉的收缩和舒张内径进行检测,并计算动脉的扩张性、紧张度和僵硬度。结果与对照组和非代谢综合征组比较,代谢综合征组患者颈总动脉扩张性、紧张度明显下降(P<0.01),僵硬度明显升高(P<0.01);平均内膜中层厚度增厚(P<0.01);等级相关分析发现,左、右颈总动脉的扩张性和紧张度与代谢综合征成分数目呈负相关(P<0.01),左、右颈总动脉的僵硬度与代谢综合征成分数目呈正相关(P<0.01)。结论代谢综合征患者颈动脉的弹性降低,动脉硬化加剧;颈动脉超声可以作为评价代谢综合征患者心血管病危险性的无创性方法。

Distensibility,Strain and Stiffness of Common Carotid in the Patients with Metabolic Syndrome

Aim To explore the change of distensibility,strain and stiffness of carotid in the patients with metabolic syndrome(MS). Methods The systolic and diastolic diameters of common carotid and carotid intima-media thickness(IMT) were measured with high-resolution ultrasonography in 33 healthy samples,76 nonMS samples and 83 MS samples,and arterial distensibility,arterial strain and arterial stiffness were calculated. Results The arterial distensibility and arterial strain were significantly decreased(P<0.01) whereas arterial stiffness and mean IMT of common carotid artery were significantly elevated in MS group(P<0.01) compared with control group and non-MS group.The arterial distensibility and arterial strain of right and left common carotid were negatively related to the number of MS components(P<0.01),but the arterial stiffness of right and left common carotid were positively related to the number of MS components (P<0.01). Conclusion Individuals with MS had decreased elasticity of artery, and accelerated arteriosclerosis.Ultrasonography of carotid artery was indicated to be an effective noninvasive method to detect cardiovascular disease in patients with MS.