| 11C-MET PET在脑肿瘤中的应用 |
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| 引用本文： | 华逢春. 11C-MET PET在脑肿瘤中的应用[J]. 国际放射医学核医学杂志, 2002, 26(1): 1-4 |
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| 作者姓名： | 华逢春 |
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| 作者单位： | 复旦大学附属华山医院核医学科 |
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| 摘 要： | 1C_MET(11C_蛋氨酸)是目前用于肿瘤PET最多的氨基酸类显像剂之一 ,它能反映体内氨基酸的转运、肿瘤氨基酸的代谢及蛋白质的合成。11C_METPET能用于脑肿瘤的诊断、区分肿瘤复发及放射性坏死 ,早期评价治疗效果 ,尤其对肿瘤周边组织及低度恶性肿瘤的诊断要优于18F_FDGPET、CT和MRI
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| 关 键 词： | 脑肿瘤 正电子发射断层显像 11C_蛋氨酸 |
| 文章编号： | 1001-098X(2002)01-0001-04 |
| 修稿时间： | 2001-06-27 |
The applications of 11C-MET PET in brain tumor |
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| HUA Feng _ chun. The applications of 11C-MET PET in brain tumor[J]. International Journal of Radiation Medicine and Nuclear Medicine, 2002, 26(1): 1-4 |
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| Authors: | HUA Feng _ chun |
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| Abstract: | C_methionine(MET), an amino acid, is the most widely used radiopharmaceutics which can reflect transport metabolism of amino acid in vivo, and synthesis of protein in tumor. 11C_MET PET can be used for evaluation of brain tumor: detection of tumor, differential diagnosis between recurrence and radiation necrosis and early evaluation of response to treatment. Especially, for the definition of tumor margin and detection of low_grade tumors, PET with 11C_MET is better than PET with 18F_FDG or other modalities such as CT and MRI. |
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| Keywords: | brain tumor positron emission tomography 11C_methion |
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