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Possible therapeutic role of vitamin D3 in aggressive fibromatosis
Authors:Ferah Yildiz  Ayse Kars  Mustafa Cengiz  Ugur Selek  Murat Gurkaynak  Lale Atahan I
Affiliation:1 Department of Radiation Oncology and 2 Department of Medical Oncology, Hacettepe University Faculty of Medicine, 06100, Ankara, Turkey
Abstract:Desmoids, also known as aggressive fibromatoses, are locallyinvasive tumors that are intermediate in their biological behaviorthat lies between benign fibrous proliferations and low-gradefibrosarcomas. In this report, we present a case of a youngfemale patient with a huge tumoral mass located in the rightshoulder region that recurred after total resection and wasresistant to radio-chemo-hormonal therapy. Eventually, she respondedto 1,25-(OH)2-vitamin D3 treatment.
Keywords:aggressive fibromatosis    vitamin D3
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