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Toll样受体对肝功能衰竭的作用
引用本文:黄瑜,陈永平. Toll样受体对肝功能衰竭的作用[J]. 国际流行病学传染病学杂志, 2006, 33(4): 278-280
作者姓名:黄瑜  陈永平
作者单位:325003,温州医学院附属第一医院传染科;325003,温州医学院附属第一医院传染科
摘    要:Toll样受体(TLR)是新近研究的热点,TLR作为脂多糖(lipopolysaccharide,LPS)信号转导受体,在与LPS反应时可形成一个由TLR、MD_2和CD14构成的复合体,参与信号转导,激活下游细胞因子,而TLR可通过各种方式参与肝功能衰竭的过程,与肝功能衰竭有着密切的关系。

关 键 词:肝功能衰竭  Toll样受体  信号转导
收稿时间:2005-10-17
修稿时间:2005-10-17

The contribution of toil-like receptor in liver failure
HUANG Yu,CHEN Yong-ping. The contribution of toil-like receptor in liver failure[J]. International Journal of Epidemiology and Infectious Disease, 2006, 33(4): 278-280
Authors:HUANG Yu  CHEN Yong-ping
Affiliation:Department of Infectious Diseases, the First Affiliated Hospital, Wenzhou Medical College, Wenzhou 325003, China
Abstract:Toll-like receptors have attracted much attention of people.One of them, toll-like receptor(TLR), is the receptor transducting signal of LPS. Combining LPS, TLR4 can take part in signal transduction and active downstream cytokine with MD-2,CD14. However, TLR can attend the program of liver failure in many ways and lead to liver failure.
Keywords:Liver failure  Toll-like receptor  Signal transduction
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