肿瘤标志物对老年恶性胸腔积液诊断价值探讨

目的 探讨糖类抗原(CA50.CA19—9.CA125),癌胚抗原(CEA)对老年恶性胸腔积液的诊断价值。方法 测定老年良性、恶性胸腔积液患者血清和胸水中CEA、CA50、CA19—9、CA125水平,比较其敏感性、特异性、准确性。结果 恶性胸腔积液患者血清中CEA、CA50、CA19—9、CA125和胸水中CEA、CA50、CA19—9水平显著高于良性胸腔积液患者,且CEA和CA50、CA19—9、CA125联合检测准确性高于单项检测。结论 CEA、CA50、CA19—9、CA125检测对老年恶性胸腔积液诊断有意义,联合检测意义更大。

Evaluate tumor marker in the diagnosis of aged patients with malignant pleural effusion

Objective To evaluate CA50,CA19-9CA125 and CEA in the diagnosis of the aged pa-tients with malignant pleural effusion. Methods To measure the 4 tumor marker in pleural fluid and serum of aged patients with malignant effusion and benign effusion and compare the sensitivity,the correct-ness and the specialty of the 4 tumor markers. Results serum level of CEA CA50 CA19-9 CA125 and pleural level of CEA CA50 CA19-9 in the patients with malignant effusion were significantly higher than in the those with benign,the sensitivty of CEA combined with CASO and CA19-9 was higher than one of those. Conclusions Measuremants of CEA,CA19-9.CA125 is useful diagnosis in the aged patients with malignant pleural effusion and measurement combinated of those increases sensitivity in diagnosis.