94例真菌性角膜炎患者的病原菌临床分析

目的了解海南地区真菌性角膜炎病原菌的种类和构成情况,分析真菌性角膜炎患者的流行病学特征,并指导临床个体化治疗。方法对2010年3月至2011年2月在我院眼科门诊就诊的94例刮片镜检阳性的真菌性角膜炎患者的病例进行回顾性分析,细菌培养鉴定菌种。结果海南地区真菌性角膜炎在10~12月份为高发季节,以镰刀菌感染(61例,64.9%)为主,除此之外还有烟曲霉菌(28例,29.8%)、链格孢霉菌(2例,2.1%)、待鉴定菌种(3例,3.2%)。结论真菌性角膜炎是严重的致盲性眼病,应提高对该病的认识和诊断水平,镰刀菌为目前海南地区真菌性角膜炎的主要致病菌。

Pathogenic analysis of fungal keratitis:a report of 94 cases

Objective To learn the pathogenic features of fungal keratitis in Hainan province and analyzed its epidemiological characters, thus provide guidance for individualized treatment. Methods A retrospective study was carried out in 94 patients diagnosed as having fungal keratitis in the Department of Ophthalmology from March 2010 to February 2011. The strains were identified by bacterial culture. Results Fungal keratitis highly occurred from Sep. to Dec. Sixty-one cases were detected with Fusarium (64.9%), 28 with Aspergillus fumigatus (29.8%), 2 cases with Alternaria alternata (2.1%), and 3 cases needed further identification (3.2%). Conclusion Fusarium is a dominant pathogen of fungal keratitis in Hainan province.