Effectiveness of oral appliances versus continuous positive airway pressure in treatment of OSA patients: An updated meta-analysis |
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| Authors: | Menghan Zhang Yuehua Liu Yuanshun Liu Fengyang Yu Shaowen Yan Lulu Chen |
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| Affiliation: | 1. School of Stomatology, Zhejiang Chinese Medical University, Hangzhou, China;2. Shanghai Stomatological Hospital, Fudan University, Shanghai, China;3. The Second Clinical Medical College, Zhejiang Chinese Medical University, Hangzhou, China;4. Orthodontic Center, Perfect Dental Care, Golden Mansion, Hangzhou, China;5. Zhejiang Provincial People’s Hospital, Hangzhou, China |
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| Abstract: | Objective: To update the meta-analysis comparing the effectiveness of oral appliance (OA) with continuous positive airway pressure (CPAP) in treating patients with obstructive sleep apnea (OSA). Methods: PubMed, ISI Web of Knowledge, Ovid, EBSCO Dentistry & Oral Science Source, The Cochrane Library, and Embase database were searched for RCTs until 23 May 2017. Meta-analyses were performed using RevMan 5.3. Results: Sixteen RCTs were included. Compared with OA, CPAP significantly decreased AHI, min SaO2, ARI, ESS (p < 0.05), with no significant difference in REM%, FOSQ, BP (p ≥ 0.05). OA significantly improved REM% in the severe groups and ESS in the adjustable OA group (p < 0.05). OA shared greater preference. Conclusion: Even though CPAP can better decrease the severity of OSA, more patients opted for OA, which showed better results in severe patients, especially adjustable OA. |
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| Keywords: | Meta-analysis obstructive sleep apnea oral appliance continuous positive airway pressure |
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