A ROLE FOR ANTIBODIES IN TUMOR IMMUNITY |
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| Authors: | RONALD C. KENNEDY MICHAEL H. SHEARER |
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| Affiliation: | Department of Microbiology and Immunology, Texas Tech University Health Sciences Center, Lubbock, Texas |
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| Abstract: | Recent advances have demonstrated the clinical utility of specific monoclonal antibodies that recognize tumor-associated antigens on the surface of the tumor cell in the treatment of breast cancer and B cell lymphoma in humans. In addition to these studies, an experimental tumor model, where antibodies that recognize a viral-encoded tumor-specific antigen play a major role in tumor immunity, will be discussed. Together, these studies implicate antibodies as a means of providing tumor immunity against some cancers. The necessity for designing cancer vaccines that induce antibodies with specificity for antigens on the tumor cell will be discussed. antibodies immunity tumors |
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