早期梅尼埃病患者前庭诱发肌源性电位的特征

目的 建立听力室前庭诱发肌源性电位（VEMPs）潜伏期、耳间潜伏期差值、振幅比及耳间不对称率等参数的正常值，分析早期梅尼埃病患者的VEMPs特征。方法 随机选取听力正常的健康成人39例，用于建立VEMPs正常值范围并用作健康对照；对单侧发病的早期梅尼埃病患者37例，行双侧VEMPs检测，分析其VEMPs特征。结果 37例单侧发病的早期梅尼埃病患者中，患侧未能引出者11例，双侧未能引出者4例，另外15例患侧VEMPs的异常表现可为p13或n23潜伏期延长、耳间潜伏期差值延长、振幅增强或减弱等，总异常率为81.08%。结论 当VEMPs的耳间潜伏期差值表现为延长、振幅表现为增强或减弱时，对早期梅尼埃病的诊断有显著意义。

Characteristics of vestibular evoked myogenic potentials in patients at early stage of Meniere’s disease

Objective To establish the normal values of vestibular evoked myogenic potentials（ VEMPs） in the patients at early stage of Meniere＇s Disease（ MD）,including the latency,interaural latency,rate of amplitude and interaural amplitude difference（ IAD） ratio. Methods 39 cases of healthy adults with normal hearing were chosen as the controls,while 37 patients with unilateral Ménière＇s disease at early stage were enrolled into the MD group. The characteristics of VEMPs in MD group were analyzed. Results In MD group,the rate of abnormal VEMPs was 81. 08%,in which VEMPs was not present on affected side in 11 cases and on both sides in 4 cases. The characteristics of the VEMPs consisted of prolonged latency of p13 or n23,prolonged IAL difference,and augmented or depressed amplitude. Conclusion The prolonged IAL difference and altered amplitudes of VEMPs are prominent in the early stage of Meniere＇s Disease.