颈动脉内膜增厚和斑块形成对冠心病的诊断价值

目的 探讨颈动脉内膜增厚及斑块形成与冠心病的相关性.方法 住院患者共131例,其中冠心病组54例,冠心病高危组46例,对照组31例,测量颈动脉管壁内-中膜厚度、斑块长度及厚度,所得数据用SPSS 17.0软件包行统计学处理.结果 冠心病组与冠心病高危组颈动脉内膜增厚的发生率与厚度之间差异均无统计学意义(均P＞0.05),而以上两组与对照组之间颈动脉内膜增厚的发生率与厚度之间差异均有统计学意义(t=3.26、3.48,均P＜0.05),三组之间的颈动脉斑块积分及斑块分级差异有统计学意义(F=4.28,P＜0.05).结论 颈动脉内膜增厚及斑块形成是冠心病的独立危险因素,可以预测冠心病的发生及发展,尤其以颈动脉斑块的特异度更高.

Diagnostic value of carotid artery intima-media thickness and plaque formation for coronary heart disease

Objective To investigate the relationship between carotid intima-media thickness （IMT）and plaque extent of carotid artery with coronary heart disease （CHD）. Methods 131 inpatients were divided into 3 groups, in which 54 cases of coronary heart disease group ,46 cases of risk group with coronary heart disease,31 cases of control group. The carotid wall IMT, plaque length and thickness was measured by Color Doppler ultrasound. The obtained data using SPSS 17.0 software for statistical processing. Results Carotid intimal thickening and the inci- dence had no significant difference between the group of coronary heart disease and risk group with coronary heart dis- ease risk（ all P 〉 0.05 ）, carotid artery IMT and incidence rate between the above two groups and the control group had statistical differene （t = 3.26,3.48, all P 〈 0.05 ） , and the three groups of carotid artery plaque score and plaque classification were statistically significant（ F = 4.28 ,P 〈 0.05 ）. Conclusion Carotid IMT and plaque formation was the independent risk factor of CHD, and it could predict the occurrence and development of CHD, especially in carotid artery plaque specificity is higher, in the primary hospital could be used as the auxiliary examination method of CHD.