糖尿病酮症酸中毒合并胰酶升高36例分析

目的 探讨糖尿病酮症酸中毒(DKA)患者血淀粉酶、脂肪酶升高的程度及其与急性胰腺炎(AP)的关系.方法 将36例糖尿病酮症酸中毒合并胰酶升高患者根据腹部CT结果分为非胰腺炎组20例和胰腺炎组16例.测定并比较两组患者血淀粉酶、尿淀粉酶、血脂肪酶水平.结果 血淀粉酶非胰腺炎组为(275.0±10.5)U/L,胰腺炎组为(615.4±17.8)U/L,两组差异有统计学意义(P＜0.01),而血脂肪酶非胰腺炎组为(2125.0±50.4)U/L,胰腺炎组为(2021.0±19.8)U/L,两组差异无统计学意义(P＞0.05),血淀粉酶与腹CT结果符合性高.结论 单纯糖尿病酮症酸中毒可引起胰酶升高,在诊断急性胰腺炎的胰酶检查中,血淀粉酶的特异性较脂肪酶高.

Analysis of 36 cases of diabetic ketoacidosis with increased trypsin

Objective To explore the rising degree of hemodiastase, lipase and the relationship with acute pancreatitis with diabetic ketoaeidosis （DKA）. Methods 36 diabetic ketoacidosis patients with increased trypsin were divided into non panereatitis group （20 cases） and pancreatitis group （16 cases） based on the results of abdom- inal CT. And the blood amylase, urine amylase, blood fat enzyme levels of the two groups were measured and compard. Results The blood amylase of the panereatitis group was （ 275.0 ± 10.5 ） U/L, and that of pancreatitis group was （615.4 ± 17.8）U/L, the difference between two groups was obvious （P 〈 0.01 ）;The blood lipase of pancreatitis group was （2125.0 ±50.4）U/L,and that of pancreatitis group was （2021.0 ±19.8） U/L,there was no significant difference between the two groups （ P 〉 0.05 ）. The blood amylase and abdominal CT results compliance high. Conclusion Pure DKA can cause diabetes pancreatic enzyme increases, and in the diagnosis of acute pancreatitis, the specificity of blood amylase is high.