Abstract: | Experimental pseudotuberculosis arthritis was reproduced by means of antigenic irritation of the knee joint in the presence of specific sensibilization. Pathomorphology is characteristic of the acute exudative-proliferative synovitis and periarthritis. The results obtained allow one to draw the conclusion on the infectious-allergic genesis of the joint involvement in pseudotuberculosis. The stages in the allergic responses of the synovial membrane with subsequent development of early and late immune inflammation are revealed. |