| 外周血染色体与相关疾病的关系 |
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| 引用本文： | 张莲爱,黎培石,伍桂群,黎华文,何连珠. 外周血染色体与相关疾病的关系[J]. 中国妇幼保健, 2006, 21(9): 1239-1241 |
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| 作者姓名： | 张莲爱 黎培石 伍桂群 黎华文 何连珠 |
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| 作者单位： | 广东省肇庆市第一人民医院,526021 |
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| 摘 要： | 目的:探讨有关疾病与染色体的关系。方法:外周血细胞培养,G显带对726例有关疾病(不良孕育史夫妇504例,先天大脑发育不全129例,不育、无精症70例,原发性闭经23例)进行了外周血染色体细胞遗传学分析。结果:检出异常染色体160例,异常率22·04%。其中数目异常99例,异常率13·64%;结构异常38例,异常率5·23%;“正常变异”25例,变异率3·44%。结论:染色体数目或结构异常均会造成不同程度的不良后果。
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| 关 键 词： | 外周血细胞培养 染色体 核型异常 |
| 文章编号： | 1001-4411（2006）09-1239-03 |
| 收稿时间： | 2005-04-14 |
| 修稿时间： | 2005-04-14 |
Relationship between peripheral blood chromosome and the related diseases |
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| ZHANG Lian - Ai, LI Pei -Shi, WU Gui - Qun,et al.. Relationship between peripheral blood chromosome and the related diseases[J]. Maternal and Child Health Care of China, 2006, 21(9): 1239-1241 |
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| Authors: | ZHANG Lian - Ai LI Pei -Shi WU Gui - Qun et al. |
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| Affiliation: | The First Hospital of Zhaoqing 526021, Guangdong , China |
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| Abstract: | Objective:To study the relationship between the related diseases and chromosome.Methods:Peripheral blood chromosome was cultivated to conduct spectrum analysis and karyotype analysis of parallel chromosome in 726 cases, including 504 cases of abnormal pregnancy and abnormal child delivery, 129 cases of retard babies, 70 cases of infertility or lack of sperm, 23 cases of primary amenorrhvea.Results:Of 160 cases of karyotype disorder, abnormal rate was 22%.99 were numerical abnormalities, 38 structural abnormalities, 25 natural dissociation.Conclusion:Numerical or structural aberrance in chromosome will lead to poor outcome with different degrees. |
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| Keywords: | Venule blood chormosome cultivating Chromosome Abnormal karyotype |
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