结节性硬化症的MR诊断

目的探讨TS的MR影像特征.材料和方法本组17例.采用MR T1WI横断面、矢状面及T2WI横断面扫描.结果室管膜下结节17例,共119个结节,主要分布于侧脑室前角、体部及三角区外侧壁上,T1WI以等信号、高信号为主(91/119),T2WI以混杂高信号最多见.皮质结节12例,共120个结节,主要分布于额叶、顶叶(93/120).白质病灶8例,病灶呈放射带状、楔形及非特异性病灶,T1WI呈等低信号,T2WI呈高信号.室管膜下巨细胞星形细胞瘤3例,均位于室间孔区,T1WI呈等低信号,T2WI呈混杂高信号,增强后明显均匀强化.结论MRI是结节性硬化症最好的检查方法之一,其MR影像表现具有特征性.

MR Diagnosis of Tuberous Sclerosis

Purpose: To analyze the characters of tuberous sclerosis on MRI. Materials and Methods: There were 17 cases in this study. All the patient were examined by T 2WI in the axial plane or T 1WI in both axial plane and sagittal section. Results: Therer were 119 subpendymal nodules in the 17 patients. They were mainly located at wall of the anterior horn, body and triangular area of the lateral ventricles. They showed variable homogenerous or heterogenerous signal intensity, appearing iso hyperintense to gray or white matter and rarely hypointense to white matter on T 1WI and hyper hypointense to gray or white matter on T 2WI. Cortical tubers were detected in 12 of 17 patients. A total of 120 tubers were identified in the 17 patients. The numbers of tubers showed a gradual decline from frontal lobe to patietal lobe to temporal lobe to occipital lobe. Lesions of the white matter were found in 8 of the 17 patients. The white matter lesions displayed three distinct patters, such as thin radial bands, wedge shaped lesion, and nonspecific foci. These lesions were iso to hypointense to white matter on T 1WI and hyperintense to gray and white matter on T 2WI. There Subependymal Giant Cell Astrocytomas were seen in 3 of 17 patients. All three SGCAs were located at or near the foramina of Monro. All tumors were enhanced in a nearly homogeneous fashion. Conclusion: MRI is one of the best method for diagnosing tuberous sclerosis. Its manifestations on MRI are typical and characteristic.