Automatische Bestimmung der Delta-Amino-Laevulinsäure im Urin

Summary In a group of workers exposed to lead and a group of people representing the general urban and rural population of Finland the serum creatinine (S-Great) concentrations of 1342 men and 377 women, glutamic oxaloacetic acid transaminase (S-GOT) activities of 1464 men and 510 women, and glutamic pyruvic acid transaminase (S-GPT) activities of 377 men and 235 women were compared to the respective blood lead (B-Pb) concentrations. There was no correlation between S-Great, S-GOT, or S-GPT and B-Pb levels or exposure time. Only a random variation was found in the values of S-Great, S-GOT between different lead exposure categories. This finding does not exclude the possibility of either renal or liver damage at the B-Pb levels studied here, but it indicates that the measurement of S-Great, S-GOT and S-GPT cannot be recommended as a routine screening procedure for lead-exposed workers.Abbreviations B-Pb blood lead - S-GOT serum glutamic oxaloacetic transaminase - S-GPT serum glutamic pyruvic acid transaminase - S-Great serum creatinine