| 金菊花乙酸乙酯提取物对大鼠实验性肝损伤的影响 |
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| 引用本文： | 芦金清,李竣,彭少平,刘毅.金菊花乙酸乙酯提取物对大鼠实验性肝损伤的影响[J].中西医结合肝病杂志,2001,11(6):345-346. |
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| 作者姓名： | 芦金清 李竣 彭少平 刘毅 |
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| 作者单位： | 湖北中医学院,武汉,430061 |
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| 摘 要： | 目的：观察金菊花乙酸乙酯提取物（EAEDM）对肝损害的防护作用，方法：建立大鼠急性乙醇中毒肝损害模型，通过大鼠灌胃EAEDM，以对照组对照，测定血清过氧化脂质（MDA），谷胱甘肽过氧化物酶（GSH－PX），血清谷丙转氨酶（ALT）和血清谷草转氨酶（AST）的含量，结果：EAEDM能降低MDA，ALT和AST的活性，减少肝脏MDA的生成，增加GSH－PX的活性，结论：EAEDM对肝损伤具有防护作用。
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| 关 键 词： | 乙酸乙酯提取物 金菊花 急性乙醇中毒 大鼠模型 肝损伤 中药 药理 |
| 修稿时间： | 2001年10月16 |
Effect of Ethyl Acetate Extract of Dendranthema Morifolium on Experimental Liver Injury of Rats |
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| LU Jingqing,LJ Jun,PENG Shaoping,et al..Effect of Ethyl Acetate Extract of Dendranthema Morifolium on Experimental Liver Injury of Rats[J].Chinese Journal of Integrated Traditonal and Western Medicine on Liver Diseases,2001,11(6):345-346. |
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| Authors: | LU Jingqing LJ Jun PENG Shaoping |
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| Institution: | LU Jingqing,LJ Jun,PENG Shaoping,et al. Hubei College of Traditional Chinese Medicine |
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| Abstract: | To observe the protective action of ethyl acetate extract of Dendranthema Morifolium on liver
injury in rats. Methods: In this study, the acute ethylism rat model was used. Results: The ethyl acetate extract of Dendranthema Morifolium could inhibit the activities of MDA, ALT, AST; decrease the formation of MDA in liver; increase the activity of GSH-PX. Conclusion: The ethyl acetate extract of Dendranthema Morifolium have protective action on liver injury. |
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| Keywords: | Ethyl Acetate Extract Dendranthema Morifoiium Acute Ethylism Rat Model Liver injury |
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