大鼠肾小囊上皮细胞发生发育的变化

目的探讨胚胎及生后大鼠肾小囊上皮细胞发生发育的变化规律。方法采用光镜连续切片技术,电镜制作技术,并结合体视学分析方法,对不同发育阶段大鼠肾小囊上皮细胞发育的变化进行形态学观察和体视学测量。结果上皮细胞在发育过程中,细胞排列从紧密到分散,胞质从少到多,胞体从柱状到扁平,细胞突起从无到有,从少到多。结论随着发育过程中形态的变化,上皮细胞逐渐参与了肾小体滤过屏障的组成。

The change of the origin and development of the epithelial cell in rat renal capsule

Objective To explore the change of the origin and development in rat renal capsule's epithelial cell at embryonic and postnatal day.Methods Light paraffin series section technology and electron microscope combined with stereology methods were used to observe and measure the development of the rat renal capsule's epithelial cell at different developmental stages.Results In the development of the epithelial cell,the cell was arranged from thickness to dispersion,the amount of cytoplasm was from small quantity of large quantity.The cell body was from column to thin and flat form,cell gibbosity grew out of nothing and changed from small quantity to large quantity,the extracellualr space expanded from small to large.Conclusion With the morphological variation in its development,the epithelial cell was involved in the formation of glomerular filtration barrier.