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Brain metabolism is significantly impaired at blood glucose below 6 mM and brain glucose below 1 mM in patients with severe traumatic brain injury
Authors:Roman Meierhans  Markus Béchir  Silke Ludwig  Jutta Sommerfeld  Giovanna Brandi  Christoph Haberthür  Reto Stocker  John F Stover
Affiliation:1.Surgical Intensive Care,University Hospital Zürich,Zürich,Switzerland;2.Ospedale Maggiore Policlinico Milano,Via Francesco Sforza, 28,Milano,Italy;3.Surgical Intensive Care,Luzerner Kantonsspital,Switzerland
Abstract:

Introduction  

The optimal blood glucose target following severe traumatic brain injury (TBI) must be defined. Cerebral microdialysis was used to investigate the influence of arterial blood and brain glucose on cerebral glucose, lactate, pyruvate, glutamate, and calculated indices of downstream metabolism.
Keywords:
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