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Passive immunization targeting the N-terminal projection domain of tau decreases tau pathology and improves cognition in a transgenic mouse model of Alzheimer disease and tauopathies
Authors:Chun-ling Dai  Xia Chen  Syed Faraz Kazim  Fei Liu  Cheng-Xin Gong  Inge Grundke-Iqbal  Khalid Iqbal
Affiliation:1. Department of Neurochemistry, Inge Grundke-Iqbal Research Floor New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY, 10314, USA
2. Neural and Behavioral Science Graduate Program, State University of New York (SUNY) Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY, 11203, USA
3. SUNY-IBR Center for Developmental Neuroscience (CDN), 1050 Forest Hill Road, Staten Island, NY, 10314, USA
Abstract:
Keywords:
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