广东省某高校2004年新生乙肝病毒感染调查

[目的]了解高校入学新生乙肝病毒感染情况,为高校防治乙肝采取有效措施提供依据,减少和控制乙肝的传播流行.[方法]用酶联免疫吸附试验（ELISA）检测HBsAg,对HBsAg阳性者进行其他4项乙肝血清标志物检测,即乙肝表面抗体（抗-HBs）、e抗原（HBeAg）、e抗体（抗Hbe）和核心抗体（抗-HBc）.用速率法检测丙氨酸氨基转移氨酶（ALT）、门冬氨酸氨基转移酶（AST）.[结果]2 671名2004年入学新生HBsAg阳性率为16.66%.其中男生HBsAg阳性率为18.73%,女生HBsAg阳性率为12.11%,二者差异有统计学意义（P＜0.01）.ALT十AST升高伴HBsAg阳性有52人,占阳性人数的11.69%.[结论]广东江门某高校2004年新生HBsAg阳性率较高,高校应加强传染源的管理,在学生中进行乙型肝炎知识的健康教育,提高学生的自我保护意识和防病意识,定期进行肝功能及乙肝5项指标检查,对易感染者进行乙肝疫苗的接种.

Analysis on Hepatitis B Virus Infection of New Students from One University of Guangdong in 2004

[Objective]To understand the situation of hepatitis B virus infection among new students in university in order to make effective measure for its control and prevention.[Methods]To test HBsAg by enzyme-linked immunoadsorbent assay(ELISA) for each students,and test HBsAb,HBeAg,HBeAb and HBcAb by ELISA and test ALT,AST for HBsAg positive ones.[Results]HBsAg positive rate of new students was 16.66%,with 18.73% for boys and 12.11% for girls,the difference between them had statistic significance(P<0.01).The HBsAg positive persons with ALT+AST rising accounted for 11.69% of positive ones.[Conclusion]HBsAg positive rate of new students was higher in one university in Jiangmen Guangdong.The management of infection source should be strengthened in the university,and the knowledge of HB should be promotioned among students.