结节病的18F-FDG PET/CT的诊断价值

目的探讨和分析结节病的18F-FDG PET/CT表现,为结节病的正确诊断提供依据。方法回顾性分析16例的结节病患者的临床资料及PET/CT表现,分析总结病变累及部位、大小、标准摄取值(SUV)特点。结果有咳嗽、胸闷等症状者12例,无症状者4例;淋巴结累及者16例:15例累及纵隔及双肺门淋巴结,5例累及锁骨上窝淋巴结,4例累及腹腔或腹膜后淋巴结,2例累及腹股沟淋巴结;有临床症状者淋巴结大小为(27.42±8.92)mm,无临床症状者(26.25±8.54)mm,两者无统计学差异(P<0.918)。两组代谢均有不同程度的增加,有临床症状者SUV最大值(8.34±3.54),无临床症状者SUV最大值(4.20±2.56),两者无统计学差异(P<0.273)。结外脏器累及:双肺多发结节影或斑片影8例,胸膜累及2例,皮肤累及1例,所有结外病灶代谢均有增加,SUV最大值为1.5～4.5不等。结论 PET/CT能准确地反映结节病的病灶分布范围和病灶活性,为临床诊断和治疗提供依据。

Diagnostic value of 18F-FDG PET/CT for Sarcoidosis

Objective To investigate and analyze 18F-FDG PET / CT features of sarcoidosis,and improve the diagnostic accuracy of this benign disease.Methods A retrospective analysis of clinical data of 16 cases of sarcoidosis and PET / CT performance,analyze and summarize the lesions involving the location,size,standard uptake value(SUV) features.Results ①symptoms of cough,chest tightness and other symptoms of 12 cases,4 cases of those who are asymptomatic.②involved lymph nodes of 16 cases: 15 cases involving the mediastinum and lung hilar lymph nodes,5 cases involving the supraclavicular fossa lymph nodes,4 cases involving the abdominal membrane lymph nodes,2 cases involving the inguinal lymph nodes.The clinical symptoms of lymph node size was(27.42±8.92)mm,(26.25±8.54)mm clinical symptoms,there was no significant difference(P<918).The metabolism of two groups were increased in varying degrees of clinical symptoms SUVmax of(8.34±3.54),no clinical symptoms SUVmax(4.20±2.56),there was no significant difference(p.273).Extranodal organs involved: multiple lung nodules or plaques,shadow 8 cases involving the 2 cases,pleural,skin involving 1 cases,increased in all extranodal lesions metabolism,SUVmax value ranging from 1.5 to 4.5.Conclusions PET / CT can accurately reflect the scope and focus of activity of sarcoidosis lesion distribution,provide a basis for clinical diagnosis and treatment.