| 可生物降解长效注射给药系统的研究进展 |
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| 引用本文： | 李坤,刘晓君,陈庆华. 可生物降解长效注射给药系统的研究进展[J]. 中国医药工业杂志, 2012, 43(3): 214-221 |
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| 作者姓名： | 李坤 刘晓君 陈庆华 |
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| 作者单位： | 中国医药工业研究总院药物制剂国家工程研究中心,上海,200437 |
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| 摘 要： | 可生物降解长效注射给药系统具有局部注射给药一次后能持续几天甚至几个月释药的特点,日益受到生命科学研究者和临床医生的重视.本文介绍了长效注射给药系统的研发历程、生物降解聚合物的类型与特性以及该剂型的临床应用现况,同时客观评价了可生物降解注射剂的应用前景和存在问题.
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| 关 键 词： | 长效注射给药系统 生物可降解 综述 |
Research and Development of Biodegradable Long-action Injectable Drug Delivery System |
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| LI Kun , LIU Xiaojun , CHEN Qinghua. Research and Development of Biodegradable Long-action Injectable Drug Delivery System[J]. , 2012, 43(3): 214-221 |
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| Authors: | LI Kun LIU Xiaojun CHEN Qinghua |
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| Affiliation: | (National Pharmaceutical Engineering Research Center,China State Institute of Pharmaceutical Industry,Shanghai 200437) |
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| Abstract: | Due to the distinctive advantage of drug sustained-release for several days to months after local injection,biodegradable long-action injectable drug delivery system(DDS) has got more and more attention either in the life science or in the clinic.The purpose of this paper is to review the procedure in R&D of the DDS,the styles and specific properties of biodegradable polymers as well as the application of the DDS in clinic.The prospect and the problems in application are evaluated. |
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| Keywords: | long-action injectable drug delivery system biodegradable review |
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