| 硬膜外罗哌卡因用于剖腹产术后镇痛的最低运动阻滞浓度 |
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| 引用本文： | 陆智杰,孙雪峰,王晓燕. 硬膜外罗哌卡因用于剖腹产术后镇痛的最低运动阻滞浓度[J]. 实用临床医药杂志, 2009, 13(9) |
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| 作者姓名： | 陆智杰 孙雪峰 王晓燕 |
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| 作者单位： | 陆智杰(第二军医大学东方肝胆外科医院,麻醉科,上海,200438);孙雪峰,王晓燕(解放军总医院第一附属医院,麻醉科,北京,100037) |
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| 摘 要： | 目的研究剖腹产术后硬膜外镇痛的罗哌卡因最低运动阻滞浓度。方法30例ASAⅠ级的择期剖腹产病人,采用上下序贯法用不同浓度罗哌卡因行硬膜外镇痛,术后12和24h评价镇痛效果和运动阻滞情况。结果罗哌卡因的最低运动阻滞浓度MMLAC为0.301%(95%可信区间0.280%~0.334%)。结论罗哌卡因用于剖腹产术后镇痛的最低运动阻滞浓度为0.301%。
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| 关 键 词： | 罗哌卡因 硬膜外镇痛 运动阻滞浓度 |
The minimal local analgesic concentration of epidural ropivacaine for cesarean patients |
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| Abstract: | Objective To determine the motor block minimal local analgesic concentration(MMLAC) of epidural ropivacaine for cesarean patients.Methods MMLAC,defined as the 50% effective concentration(EC50) of femoral articulation blockade,was determined by up-and-down sequential method in 30 patients undergoing selective cesarean.Result MMLAC of epidural ropivacaine estimated in this study was 0.301% with a 95% confidence interval of 0.280% to 0.334%.Conclusion There is a range of epidural ropivacaine concentraion to produce satisfactory analgesia with little motor block and the result of this study can help to choose a proper ropivacaine concentration for cesarean patients. |
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