Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease): report of a patient with isolated renotesticular involvement after cure of non-Hodgkin's lymphoma |
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| Authors: | I S Lossos E Okon V Bogomolski-Yahalom N Ron A Polliack |
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| Institution: | (1) Lymphoma and Leukemia Unit, Department of Hematology, Hadassah University Hospital, P. O. B. 12000, Jerusaelm IL-91120, Israel, IL;(2) Lymphoma and Leukemia Unit, Department of Pathology, Hadassah University Medical Center, Jerusalem, Israel, IL |
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| Abstract: | Sinus histiocytosis with massive lymphadenopathy (SHML) – Rosai-Dorfman disease – is a rare but well-defined benign histiocytic
proliferative disorder. We report an unusual patient, cured of non-Hodgkin's lymphoma, who presented 12 years later with renotesticular
SHML associated with IgA monoclonal gammopathy, but without any evidence of relapsed lymphoma. The genitourinary manifestations
of this disorder with massive lymphadenopathy and its rare association with malignant lymphoma are reviewed.
Received: 4 July 1996 / Accepted: 25 September 1996 |
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| Keywords: | Non-Hodgkin's lymphoma Sinus histiocytosis Massive lymphadenopathy Rosai-Dorfman diseasea Testis Kidney Monoclonal gammopathy |
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