某高校5届新生HBsAg和ALT检测结果分析

目的了解近5届大学新生乙型肝炎表面抗原（HBsAg）携带和丙氨酸氨基转移酶（ALT）的异常及变化情况，为学生乙肝的防治工作提供科学依据。方法对我校2003-2007年本科新生HBsAg和ALT的检测结果进行统计分析。结果5届29376名新生中HBsAg总的阳性率为6．78％，ALT异常率为5．45％，HBsAg阳性伴ALT异常检出率为0．80％；男生HBsAg阳性率为7．34％，女生HBsAg阳性率为4．85％，差异有统计学意义（X^2=50．05，P〈0.01）；男生ALT异常率为6．48％，女生ALT异常率为1．88％，差异有统计学意义（X^2=210．31，P〈0．01）。5届新生的HBsAg阳性率不完全相同，2003年最高，为7．24％，2007年最低，为5．97％，并呈逐年下降趋势，差异有统计学意义（X^2=9．79，P〈0．05）；5届新生的ALT异常率比较，差异有统计学意义（X^2=177．70，P〈0．01）。结论我校新生的HBsAg阳性及ALT异常情况不容乐观，男生的HBsAg阳性率和ALT异常率均明显高于女生，应给予更多关注。

Analysis of Freshmen's HBsAg and ALT Examination Data in 5 Years

Objective To know the HBsAg-carrying and ALT abnormal situation of students admitted in our u- niversity in order to provide reference for the student＇s HBV prevention and treatment work. Method To analyze by means of statistics the HBsAg and ALT examination data of students admitted in our university in 2003--2007. Results Of the 29 376 students, the rate of HBsAg-positive, ALT abnormal both HBsAg-posi- tive and ALT abnormal are 6.78%, 5.45% ,0.80%, respectively. HBsAg-positive rate of male and female are 7.34%, and 4.85%（X^2=210.31,P〈0.01）. Difference exists in each year＇s HBsAg-positive rate （X^2=9.79, P〈0.05）. with the highest rate in 2003（7.24%） and the lowest rate in 2007（5.97%）. There is a downward trend in HBsAg-positive rate year by year. The difference among each year＇s ALT abnormal rate is significant （X^2 = 177.70,P〈0.01）. Conclusions The situation of HBsAg-positive and ALT abnormal in freshmen of our school is not optimistic. Male students should be paid more atlention as both rate of HBsAg-positive and ALT abnormal of them are obviously higher than that of female.