258例儿童哮喘危险因素的Logistic回归分析

目的:探讨哮喘的相关危险因素,为儿童哮喘的防治提供参考。方法:以258例儿童哮喘患者为观察组,同时从门诊随机抽取240例无哮喘病史的人群作为对照组。应用非条件Logistic回归分析进行多因素分析。结果:单因素分析结果表明:两组间上呼吸道感染、运动、天气变化、情绪变化、饮食、鼻炎、个人过敏史、家族过敏史、家族哮喘史比较差异有统计学意义(P<0.05)。多因素分析结果表明:上呼吸道感染、运动、饮食、鼻炎、个人过敏史、家族过敏史、家族哮喘史是儿童发生哮喘的独立危险因素(P<0.05)。结论:上呼吸道感染、运动、饮食、鼻炎、个人过敏史、家族过敏史、家族哮喘史是儿童发生哮喘的独立危险因素,对这些危险因素进行必要的干预可能降低哮喘的发生率。

Logistic regression analysis on risk factors of 258 children with asthma

Objective:To explore the related risk factors of asthma,and provide reference for prevention and treatment of children with asthma.Methods:A total of 258 children with asthma were selected as observation group,meanwhile,240 cases without asthma were selected from outpatient department of the hospital as control group,non-conditional logistic regression analysis was performed for multivariate analysis.Results:The results of univariate regression analysis showed that there was statistically significant difference in the incidence of upper respiratory tract infection,sports,changes of weather,changes of emotion,diet,rhinitis,personal allergic history,family allergic history,and family asthmatic history between the two groups(P<0.05).The results of multivariate regression analysis showed that upper respiratory tract infection,sports,diet,rhinitis,personal allergic history,family allergic history,and family asthmatic history were independent risk factors of asthma in children,there was statistical significance(P<0.05).Conclusion:Upper respiratory tract infection,sports,diet,rhinitis,personal allergic history,family allergic history,and family asthmatic history are independent risk factors of asthma in children,carrying out necessary intervention measures targeting to the risk factors may reduce the incidence of asthma.