重庆市渝北区育龄妇女孕前病毒感染状况调查

目的:了解重庆市渝北区育龄妇女孕前弓形虫(TOX)、风疹病毒(RV)及巨细胞病毒(CMV)3项病毒感染状况,为优生优育工作提供依据。方法:收集2010年的1 998份育龄妇女血清标本,用ELISA法进行TOX、RV和CMV抗体检测,用SPSS11.5统计软件对资料进行分析。结果:TOX累计及新发感染率分别为2.0%和1.0%,各年龄组间TOX累计及新发感染率差异均有统计学意义(P<0.05);RV-IgG抗体阳性率为13.3%,不同年龄组育龄妇女RV抗体阳性率差异有统计学意义(P<0.05),20～30岁人群相对易感;CMV累计及新发感染率分别为14.0%和0.6%,不同年龄组育龄妇女CMV累计感染率差异有统计学意义(P<0.05),但CMV新发感染率差异无统计学意义(P>0.05)。结论:重庆市渝北区育龄妇女TORCH3项病毒感染率偏低,人群普遍易感,应积极加强对育龄妇女人群孕前TORCH检查,以达到优生目的。

Investigation on viral infection status in women of childbearing age during progestational period in Yubei district of Chongqing city

Objective:To understand the infection statuses of toxoplasmosis virus(TOX),rubella virus(RV),and cytomegalovirus(CMV) in women of childbearing age during progestational period in Yubei district of Chongqing city,and provide a basis for eugenics. Methods:A total of 1 998 serum samples of women of childbearing age in 2010 were collected,ELISA was used to detect TOX,RV,and CMV antibodies,SPSS 11.5 statistical software was used for analysis. Results:The cumulative infection rate and recent infection rate of TOX were 2.0% and 1.0%,respectively,there were statistically significant differences among the women in different age groups(P<0.05).The positive rate of RV-IgG was 13.3%,there was statistically significant difference among the women in different age groups(P<0.05),the women aged 20-30 years old were relatively susceptible.The cumulative infection rate and recent infection rate of CMV were 14.0% and 0.6%,respectively,there was statistically significant difference in cumulative infection rate of CMV among the women in different age groups(P<0.05),but there was no statistically significant difference in recent infection rate of CMV among the women in different age groups(P>0.05). Conclusion:The infection rates of TOX,RV,and CMV in women of childbearing age during progestational period in Yubei district of Chongqing city were relatively low,the population is generally liable to infection.Progestational TORCH detection should be enhanced actively among the women of childbearing age to achieve the goal of eugenics.