重型颅脑损伤患者并发高钠血症的预后分析和治疗

目的探讨重型颅脑损伤患者伴发高钠血症的预后及其治疗策略。方法回顾性分析本院67例重型颅脑损伤伴高钠血症的患者,观察其血钠升高的程度与持续时间,与患者死亡率的关系,根据血清钠的数值,将所有患者分为3组,Ⅰ组32例：血钠值为151～160mmol/L;Ⅱ组23例：血钠值为161～170mmol/L;Ⅲ组12例：血钠值〉170mmol/L。结果 3组病例比较,随着血钠的升高,血钠升高持续时间越长,患者的死亡率越高,差异具有统计学意义（P〈0.05）。结论重型颅脑损伤合并高钠血症的患者,血钠越高,持续时间越长,患者的死亡率越高,尤其当血钠水平〉160mmol/L时死亡率明显升高。

Analysis of prognosis and treatment of severe traumatic brain injury patients combined with hypernatremia

Objective To discuss the prognosis and therapeutic strategies of severe traumatic brain injury patients combined with hypernatremia.Methods Sixty-seven severe traumatic brain injury patients combined with hypernatremia were analyzed retrospectively.Blood sodium rising degree,duration and the relationship between it and mortality of patients were observed.According to the serum sodium level,all patients were divided into three groups：Ⅰgroup had 32 patients with serum sodium level of 151-160 mmol/L,Ⅱ group had 23 patients with serum sodium level of 161-170 mmol/L,Ⅲ group had 12 patients with serum sodium over 170 mmol/L.Results Compared among the three groups,with the rise of serum sodium,longer of elevated serum sodium duration,higher of patients＇ mortality,the difference was statistically significant （P 0.05）.Conclusion Mortality of severe traumatic brain injury patients combined with hypernatremia is higher with the increasing of serum sodium and longer of duration,especially when the serum sodium level 160 mmol/L,mortality increased obviously.