胎儿生长受限高危因素的Logistic回归分析

目的:探讨胎儿生长受限(FGR)发生的高危因素。方法:采用1∶1配比的病例对照研究设计,对2011年在该院分娩的276例FGR新生儿(FGR组)及276例正常体重新生儿(正常组)及其产妇病历资料进行回顾性分析。结果:FGR组与正常组在产妇年龄、文化程度、家庭月收入、吸烟、饮茶、妊娠期感染史、妊娠期合并症、妊娠期并发症、新生儿胎龄等单因素方面比较存在差异,差异有统计学意义(P<0.05);以新生儿体重为因变量,其他因素为自变量,进行非条件性的Lo-gistic多因素分析,结果显示产妇年龄、文化程度、家庭月收入、吸烟、饮茶、妊娠期感染史、妊娠期合并症、妊娠期并发症、新生儿胎龄等因素差异有统计学意义(P<0.05)。结论:产妇高龄、文化程度低、家庭月收入低,有吸烟、饮茶、妊娠期感染史,存在妊娠期合并症、妊娠期并发症及新生儿低胎龄均是FGR发生的高危因素。在孕期应针对以上高危因素积极进行针对性预防,以减少FGR的发生。

Logistic regression analysis on risk factors of fetal growth restriction

Objective:To explore the risk factors of fetal growth restriction(FGR). Methods:A 1∶1 matched case-control study was conducted.The clinical data of 276 neonates with FGR(FGR group) and 276 neonates with normal weight(normal group) born in the hospital and the parturient women in 2011 were analyzed retrospectively. Results:There were statistically significant differences in maternal age,educational level,family monthly income,smoking,drinking tea,history of gestational infection,gestational complications,and fetal age of neonates between FGR group and normal group(P<0.05).Taking neonatal weight as dependent variable,and taking the other factors as independent variables,non-conditional logistic regression analysis was conducted,the results showed that there were statistically significant differences in maternal age,educational level,family monthly income,smoking,drinking tea,history of gestational infection,gestational complications,and fetal age of neonates(P<0.05). Conclusion:High maternal age,low educational level,low family monthly income,smoking,drinking tea,history of gestational infection,gestational complications,and low fetal age of neonates are high risk factors of FGR.Active prevention targeting to the above-mentioned high risk factors during gestational period should be conducted to reduce the occurrence of FGR.