育龄妇女子宫颈人乳头状瘤病毒感染现状调查及相关因素分析

目的:了解育龄妇女生殖道乳头状瘤病毒(HPV)感染情况,探讨HPV感染相关的危险因素。方法:选择海南省人民医院妇科门诊2007年12月～2011年1月就诊2 869例育龄妇女为研究对象。对其宫颈分泌物进行21种HPV基因型分析,并采用SPSS 11.5软件进行多因素非条件Logistic回归分析HPV感染的相关危险因素。结果:2 869例妇女中,HPV阳性检出率为14.81%,多因素非条件Logistic回归分析结果表明HPV感染与初次性生活年龄过早、性伴侣数较多、性伴侣阴茎包皮过长、伴有生殖道其他感染有关。结论:初次性生活年龄过早、性伴侣数较多、性伴侣阴茎包皮过长、伴有生殖道其他感染是育龄妇女HPV感染独立的危险因素。

Investigation on current situation of cervical human papillomavirus infection in women of childbearing age and analysis of related factors

Objective:To understand the infection status of cervical human papillomavirus(HPV) infection in women of childbearing age,and explore the related risk factors.Methods:A total of 2 869 women of childbearing age were selected from gynecological department of the hospital from December 2007 to January 2011 were selected as study objects,then their cervical secretion samples were obtained to conduct 21 kinds of HPV genotypes analysis,SPSS 11.5 software was used for analyze related risk factors of HPV infection by non-conditional logistic regression analysis.Results:Among 2 869 women,the detection rate of positive HPV was 14.81%,the results of non-conditional logistic regression analysis showed that HPV infection was correlated with too early age of sex life for the first time,multiple sex parters,redundant prepuce of sexual partners,and other reproductive tract infections.Conclusion:Too early age of sex life for the first time,multiple sex parters,redundant prepuce of sexual partners,and other reproductive tract infections are independent risk factors for HPV infection.